Untitled Document

Publications
11. Wang, X.; Makal, T. A.; Zhou, H.-C. Protein Immobilization in Metal-Organic Frameworks by Covalent Binding Aust. J. Chem. 2014, 67, 1629-1631.
10. Makal, T. A.; Zhang, W.; Zhou, H.-C. Realization of Both High Hydrogen Selectivity and Capacity in a Guest Responsive Metal-Organic Framework J. Mater. Chem. A 2013, 1, 13502-13509.
9. Makal, T. A.; Wang, X.; Zhou, H.-C. Tuning the Moisture and Thermal Stability of Metal-Organic Frameworks through Incorporation of Pendant Hydrophobic Groups Cryst. Growth Des. 2013, 13 (11), 4760-4768.
8. Lu, W.; Yuan, D.; Makal, T. A.; Wei, Z.; Li, J.-R.; Zhou, H.-C. Highly Porous Metal-Organic Framework Sustained with 12-Connected Nanoscopic Octahedra Dalton Trans. 2013, 42, 1708-1714.
7. Makal, T. A.; Li, J.-R.; Lu, W.; Zhou, H.-C. Methane Storage in Advanced Porous Materials Chem. Soc. Rev. 2012, 41 (23), 7761-7779. (Featured on Back Cover)
6. Lu, W. G.; Yuan, D.; Makal, T. A.; Li, J.-R.; Zhou, H.-C. A Highly Porous and Robust (3,3,4)-Connected Metal-Organic Framework Assembled with a 90 degrees Bridging-Angle Embedded Octacarboxylate Ligand Angew. Chem. Int. Ed. 2012, 51 (7), 1580-1584.
5. Makal, T. A.; Yakovenko, A. A.; Zhou, H-C. Isomerism in Metal-Organic Frameworks: “Framework Isomers” J. Phys. Chem. Lett. 2011, 2, 1682-1689. (Featured on Cover)
4. Li, H.-Y.; Jiang, L.; Xiang, H.; Makal, T. A.; Zhou, H.-C.; Lu, T.-B. Construction of Two 3D Homochiral Frameworks with 1D Chiral Pores via Chiral Recognition Inorg. Chem. 2011, 50 (8), 3177-3179.
3. Makal, T. A.; Yuan, D.; Zhao, D.; Zhou, H.-C. In The Chemistry of Nanostructured Materials, Vol. II, Yang, P., Ed. World Scientific: Singapore 2011: pp 37-64.
2. Fang, Q.-R.; Makal, T. A.; Young, M. D.; Zhou, H.-C. Recent Advances in Mesoporous Metal-Organic Frameworks Comment. Inorg. Chem. 2010, 31, 165-195.
1. Kuppler, R. J.; Timmons, D. J.; Fang, Q.-R.; Li, J.-R.; Makal, T. A.; Young, M. D.; Yuan, D.; Zhao, D.; Zhuang, W.; Zhou, H.-C. Potential Applications of Metal-Organic Frameworks Coord. Chem. Rev. 2009, 253, 3042-3066.

Makal Research Lab at UVa-Wise

			Contact Information
			Dr. Trevor A. Makal
			Department of Natural Sciences
			1 College Ave.
			Wise, VA 24293
			Room 232 Sandridge Science Center
			Phone: (276) 376-3442
			Email: tam9k@uvawise.edu

I performed my undergraduate studies at Texas A&M University, where I earned a B.S. degree in Chemistry with a minor in Speech Communication. Under the guidance of Dr. Simon W. North, I performed my undergraduate research in the area of chemical kinetics of lower atmosphere reactions involving isoprene. I continued at TAMU with my graduate studies in the research group of Dr. Hong-Cai Joe Zhou, where I studied structure-property relationships of functional porous materials for application in hydrogen and methane storage devices, earning my Ph.D. degree in 2013. In August of 2013 I joined the faculty at The University of Virginia’s College at Wise as an Assistant Professor of Chemistry. My current research interests are in the general areas of synthesis, characterization, and application of advanced porous materials. Specifically, I am currently interested in 1) environmental remediation of aquatic environments by means of heavy metal adsorption, 2) the stepwise synthesis of metal-organic frameworks, and 3) stability and structural transformations of metal-organic frameworks.

Research Projects My research interests are based, broadly, on the synthesis, characterization, and application of advanced porous materials, primarily metal-organic frameworks (MOFs). Owing to the extensive coal mining in the Appalachia region and increased prevalence of hydraulic fracturing, as well as recent chemical and power plant waste water spills, my current research interests have become focused on the development of new porous materials for the capture of heavy metals and toxic chemicals from aquatic environments. We have been investigating the synthesis of water-stable MOFs for capture of heavy metals through application of hard-soft acid base (HSAB) theory. MOFs allow the opportunity to anchor individual binding sites to prevent aggregation and allow for investigation of binding modes and ligand proximity on the influence of heavy metal adsorption. Furthermore, the crystalline nature of MOFs allows us to thoroughly characterize and study binding phenomena through X-ray diffraction methods, as well as fine-tune pore sizes, shapes, and functionalities through ligand or metal modification strategies to enhance binding affinity and efficiency. $Description: C:\Users\tam9k\Dropbox\Class Info\Grants\ACS PRF UNI 2014\Selective Heavy Metal Capture in MOFs.png$ Other research interests include structure property relationships in MOFs (specifically as they apply to alternative fuel storage, including natural gas and hydrogen), stimuli-responsive materials for chemical toxin capture and drug delivery systems, and stepwise synthesis of advanced porous materials.
CV
Publications 11. Wang, X.; Makal, T. A.; Zhou, H.-C. Protein Immobilization in Metal-Organic Frameworks by Covalent Binding Aust. J. Chem. 2014, 67, 1629-1631. 10. Makal, T. A.; Zhang, W.; Zhou, H.-C. Realization of Both High Hydrogen Selectivity and Capacity in a Guest Responsive Metal-Organic Framework J. Mater. Chem. A 2013, 1, 13502-13509. 9. Makal, T. A.; Wang, X.; Zhou, H.-C. Tuning the Moisture and Thermal Stability of Metal-Organic Frameworks through Incorporation of Pendant Hydrophobic Groups Cryst. Growth Des. 2013, 13 (11), 4760-4768. 8. Lu, W.; Yuan, D.; Makal, T. A.; Wei, Z.; Li, J.-R.; Zhou, H.-C. Highly Porous Metal-Organic Framework Sustained with 12-Connected Nanoscopic Octahedra Dalton Trans. 2013, 42, 1708-1714. 7. Makal, T. A.; Li, J.-R.; Lu, W.; Zhou, H.-C. Methane Storage in Advanced Porous Materials Chem. Soc. Rev. 2012, 41 (23), 7761-7779. (Featured on Back Cover) 6. Lu, W. G.; Yuan, D.; Makal, T. A.; Li, J.-R.; Zhou, H.-C. A Highly Porous and Robust (3,3,4)-Connected Metal-Organic Framework Assembled with a 90 degrees Bridging-Angle Embedded Octacarboxylate Ligand Angew. Chem. Int. Ed. 2012, 51 (7), 1580-1584. 5. Makal, T. A.; Yakovenko, A. A.; Zhou, H-C. Isomerism in Metal-Organic Frameworks: “Framework Isomers” J. Phys. Chem. Lett. 2011, 2, 1682-1689. (Featured on Cover) 4. Li, H.-Y.; Jiang, L.; Xiang, H.; Makal, T. A.; Zhou, H.-C.; Lu, T.-B. Construction of Two 3D Homochiral Frameworks with 1D Chiral Pores via Chiral Recognition Inorg. Chem. 2011, 50 (8), 3177-3179. 3. Makal, T. A.; Yuan, D.; Zhao, D.; Zhou, H.-C. In The Chemistry of Nanostructured Materials, Vol. II, Yang, P., Ed. World Scientific: Singapore 2011: pp 37-64. 2. Fang, Q.-R.; Makal, T. A.; Young, M. D.; Zhou, H.-C. Recent Advances in Mesoporous Metal-Organic Frameworks Comment. Inorg. Chem. 2010, 31, 165-195. 1. Kuppler, R. J.; Timmons, D. J.; Fang, Q.-R.; Li, J.-R.; Makal, T. A.; Young, M. D.; Yuan, D.; Zhao, D.; Zhuang, W.; Zhou, H.-C. Potential Applications of Metal-Organic Frameworks Coord. Chem. Rev. 2009, 253, 3042-3066.